Cephalometric analysis is the clinical application of dental cephalometry. It is investigation of the dental and skeletal connections of a human skull. Cephalometric analysis is one of most difficult part for orthodontic and orthogenetic surgical treatments. Most of time landmark identifications is time consuming and has high dependency to operator. The aim of current investigation is to find a new approach for orthodontic landmarks identification using an artificial neural network to enhance identification of cephalometric landmarks.