The article critically reviews the recent trends in Nano finishing of macromolecule fibres like wool AN silk. The finishing strategies adopt AN eco-friendly approach aimed toward property. Plasma treatment as AN environmentally friendly method was accustomed prepare Wool/PET cloth for increased deposition of titanium oxide Nanoparticles. TiO2 Nano-particles were stabilised on the material mistreatment acid as cross linking agent within the presence of metal hypophosphite by a pad-dry-cure method. Wool materials square measure subjected to completely different surface modification strategies so as to enhance their hydrophilic , dye ability, antimicrobial, shrink proofing properties. particularly environmental friendly strategies and application of biopolymers square measure gaining importance rather than standard processes and textile chemicals. Silver Nano particles are applied on silk mistreatment cross linking binders by pad dry cure technique. Application parameters are optimized and relevant physical, structural and antimicrobial properties square measure evaluated. Mechanism of the binder action is found to be impregnation or adhesion. a completely unique fictionalisation approach has been addressed by mistreatment metal alginate (Na-Alg) assisted inexperienced silver Nano-particles (AgNPs) on ancient “Rajshahi silk” cloth via AN thorough technique. The synthesized Nano-particles and coated silk materials were characterised by completely different techniques, as well as ultraviolet–visible spectrographic analysis (UV–vis spectra), scanning microscopy (SEM), transmission microscopy (TEM), energy dispersive Xray spectrographic analysis (EDS), diffraction (XRD), thermo quantitative analysis (TGA), and Fourier rework infrared spectrographic analysis (FT-IR), that incontestible that AgNPs with a mean size of 6–10 nm were systematically deposited within the cloth surface below optimized conditions. Recent developments in numerous treatments that confer useful characteristics on wool are reviewed. Wool materials square measure subjected to completely different surface modification strategies so as to enhance their hydrophilicity, dye ability, antimicrobial, shrink proofing properties. particularly environmental friendly strategies and application of biopolymers square measure gaining importance rather than standard processes and textile chemicals. during this study, Nano chitosan particles were synthesized, applied on wool materials and compared with bulk chitosan in terms of varied properties. Agloaded chitosan Nanoparticles was conjointly synthesized and examined in terms of its medication activity by completely different application strategies.