Acalypha indica commonly known as Kuppi belongs to family Euphorbiaceae. Traditionally the plant used as a laxative, anthelmintic, cathartic and the juice is used as a speedy emetic for children and expectorant. It is used by tribal areas of Maharashtra State as rheumatic arthritis and as antihyperglycemic. However, no scientific data is available to validate the ethnobotanical claim. Keeping the above information in view, the present study has been designed to evaluate its antidiabetic activity. In the present study, hydroalcoholic extract of leaves and its fractions were studied for its anti diabetic potential in alloxan induced diabetic rats. The poly phenolic, flavonoid and flavanone contents of hydroalcoholic extract and its fractions were also determined and correlated with its anti diabetic activity.