Objective: Oxidative stress is involved in the pathophysiology of bronchial asthma. The present study was done to assess the effectiveness of practicing homeopathy in modulating free radical toxicity in bronchial asthma by measuring some parameters of oxidant stress and antioxidant defenses in blood, before and after homeopathy treatment.

Methods: In the present study, erythrocyte lipid peroxidation (LP), erythrocyte antioxidants viz., glutathione (GSH), glutathione reductase (GR), superoxide dismutase (SOD), catalase (CT) and plasma antioxidants viz., ceruloplasmin, glutathione-S-transferase (GST), vitamin C, total antioxidant activity (AOA) have been determined in 41 patients with bronchial asthma and 53 control subjects. Twenty three patients who were treated with homeopathic remedies were considered for the follow-up studies.