Gabapentin Causing Neurologic Dysfunction Leading to Falls.

Image

In this case, a middle-aged woman suffering from chronic generalized pain, depression, and fatigue was diagnosed with fibromyalgia. She suffered from multiple common comorbidities associated with fibromyalgia. For her pain, she was started on low dose of gabapentin. The medication was titrated up to an oral dose of 300 mg TID for her chronic pain. However, soon thereafter she began to suffer from ataxia and falls. The patient was tapered off of gabapentin and her symptoms improved.

A middle-aged woman presented to a university based outpatient clinic with complaints of generalized pain, low back pain, and fatigue for many years. After a thorough medical workup, she was diagnosed with fibromyalgia. A medication that was initially effective for this patient was gabapentin. However, in the setting of unrelenting pain, the dosage of gabapentin was slowly titrated up to an oral dose of 300 mg TID. About one week after being discharged from clinic, the patient and her family noted that she he had begun to have an unsteady gait and poor coordination resulting is multiple falls. The patient underwent a complete neurological workup which was noted to be negative. Vital signs were stable consistently and she had no previous history of falls. She did not have other morbidities that could explain her falls.