Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), originating from Wuhan, is spreading around the world and the outbreak continues to escalate. Patients with coronavirus disease 2019 (COVID-19) typically present with fever and respiratory illness. COVID-19 primary affects the respiratory system but central and peripheral neurological manifestations associated with severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) infection have been increasingly reported. Guillain-Barre syndrome (GBS) represents the most common cause of acute flaccid paralysis.