Sudden sensorineural hearing loss is defined as sensorineural hearing loss of 30 dB or greater in at least three contiguous frequencies as recorded in audiometry developing within a period of three days or less. Even though many etiologic factors have been brought forward, only 10-15% of cases have had their etiologies shedlight on. In most patients the sudden sensorineural hearing loss is regarded idiopathic. The approximate incidence of sudden sensorineural hearing loss is 5-20/100.000 and its potential causes that can be brought forward are infectious, autoimmune, traumatic, vascular, neoplastic, metabolic and neurologic cases. In a meta-analysis consisting of 23 idiopathic sudden sensorineural hearing loss case studies, infectious agents were reported to be the most common cause. Excluding otologic interventions, sudden hearing loss is a condition that rarely occurs after surgical operations done under general anesthesia. Most of these develop after cardiopulmonary bypass surgery where extracorporeal circulation is used. In addition to this, sudden sensorineural hearing loss has been reported to develop after surgical operations with the exclusion of otologic and cardiopulmonary interventions. In this case report, the clinical case of a patient diagnosed with multinodular goiter who developed unilateral sudden sensorineural hearing loss at an early postoperative stage after total thyroidectomy under general anesthesia together with a review of the literature wil be discussed.