Ig factor arrangement analysis victimisation PCR has become a standard apply within the characterization of human lymphoproliferative disorders. This approach is performed victimisation oligonucleotide primers recognizing a comparatively extremely preserved region of the IgH. Considering that the amplification of little genomic fragments is made even in poorly preserved material and therefore the analysis of CDR3 segments is very informative of gamma globulin factor arrangement product, we have a tendency to designed a replacement set of oligonucleotide primers recognizing the FR3 region of all members of the six gamma globulinκvariable (Vκ) familiesand thereforetheκjointregion (Jκ).