Noninvasive monitoring of liver cell transplantation

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Liver cell transplantation (LCT) is an evolving therapeutic approach for the treatment of a variety of liver diseases and is a potential future alternative to solid liver transplantation [1]. LCT is based on the administration of liver cells in suspension, which implies several conceptual advantages over whole-organ transplantation. Cells are isolated from donor livers or liver lobes that were rejected or unused for whole-organ transplantation, and this expands the donor pool for liver grafts and allows for the treatment of multiple patients with cells from one donor organ. Liver cells can be cryopreserved prior to transplantation, which enables the pooling of cells and on-demand or scheduled applications